Compound Overview
Class of Compound
Peptide
Mechanism of Action
Melanotan I is an agonist of melanocortin receptors 1, 3, 4, and 5, binding primarily to melanocortin receptor 1 to trigger melanin production.
Notable Studies
- Increased eumelanin expression and tanning is induced by a superpotent melanotropin [Nle4-D-Phe7]-alpha-MSH in humans
- Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers
- A phase II, randomised, open label pilot study to evaluate the efficacy and safety of two dosage regimens of subcutaneous bioresorbable afamelanotide implants in patients with mild to moderate acne vulgaris
Also Known As
afamelanotide, afamelanotide acetate, afamelanotide triacetate, Melanotan-1, MT-1, 1566590-77-9, CUV-1647, CUV1647 ACETATE, CHEMBL4297213, A-melanotropin, 4(nle)-7(d-phe), 75921-69-6, Scenesse
Research Applications
- Skin tanning
- Skin diseases
- Erectile dysfunction
Risks
- Limited official approval
- Mild
- Administration-related symptoms
- Many counterfeits online
Chemical Structure
Reviews
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