MK-677

MK-677 is a non-peptide ghrelin agonist and growth hormone secretagogue that has been shown to improve body composition, sleep quality, bone density, and more.

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

Compound Overview

Class of Compound:

Non-peptide ghrelin agonist and growth hormone secretagogue.

Mechanism of Action:

MK-677 is an orally-active, selective agonist of the ghrelin receptor, known to increase the secretion of growth hormone and insulin-like growth factor 1, without stimulating serum cortisol levels.

Notable Studies:

Also Known As:

MK-0677, oratrope, ibutamoren, L-163,191.

Research Applications:

Growth hormone deficiency
Body composition
Sleep quality
Anti-aging

Risks:

Increased appetite
Lack of human trials
Lack of FDA approval

Chemical Structure

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